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Pharmaceutical supply chains were not designed for that, especially for a cold chain product delivered on a weekly basis

Injection of TLR2 agonist Pam3CSK4 or TLR4 agonist lipopolysaccharide (LPS) before the striatal injection of KA significantly activated microglia and protected cortical neurons

Maintain systemic anti-inflammation: Long-acting agents like semaglutide and tirzepatide sustain anti-inflammatory effects that may deprive malignant cells of supportive inflammatory signals

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At the phylum level, liraglutide administration significantly decreased Bacteroidetes and tended to increase Actinobacteria (Fig