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In the Novo Nordisk-funded study, published on 22 October 2025, researchers from University College London (UCL) analysed data from the SELECT trial (published in 2023) of 17,604 people from 41 countries aged 45 years and over, who were overweight and had cardiovascular disease (CVD) but did not have diabetes

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As a GLP-1 receptor agonist, semaglutide binds to and activates these receptors, which is particularly effective in managing weight and controlling blood sugar levels in diabetes

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