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Ferroptosis enhanced diabetic renal tubular injury via hif-1/ho-1 pathway in db/db mice

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Preliminary data must also indicate a major therapeutic advance

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Increase frequency of glucose monitoring with changes to: insulin dosage, concomitant drugs, meal pattern, physical activity, and in patients with renal impairment or hepatic impairment or hypoglycemia unawareness

4, administration of C10:2 markedly upregulated PCNA, cyclinA, CDK2, Bcl-2, MMP2, MMP9, TGF-, while significantly dowregulated Caspase3 and Bax in PASMCs compared with PDGF-BB group, indicating that C10:2 may promote PASMCs proliferation, apoptosis inhibition and extracellular matrix remodeling in vitro