Elevated levels of HSP27 and HSP70 in breast cancer cell lines are associated with increased resistance to doxorubicin, independent of P-glycoprotein (P-gp), a key mediator of multidrug resistance (MDR)
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This point matters because it shifts the conversation away from appearance and toward long-term health outcomes such as heart attack and stroke risk
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The pathogenesis of retinoblastoma is closely linked to a p53 gene mutation and retinoblastoma gene 1 (RB1) deletion, and these two genes have been confirmed to be involved in ferroptosis