The conventional adenoma-carcinoma pathway occurs after a genomic event triggered by adenomatous polyposis coli mutation, followed by P53 loss of function or KRAS activation, whereas the serrated tumour pathway is characterised by a CpG island methylation phenotype
Eissa EM, Elkomy MH, Eid HM, Ali AA, Abourehab MAS, Alsubaiyel AM, et al
[DOI] [PMC free article] [PubMed] [Google Scholar] Ackerman C
Sp1 and Sp3 transcription factors mediate malondialdehyde-induced collagen alpha 1(I) gene expression in cultured hepatic stellate cells
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