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Neurotransmitter system interactions: Published research has examined interactions with dopaminergic, serotonergic, and GABAergic systems in animal models, contributing to its use in neurobiological research contexts

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Moreover, in the CY 2023 PFS final rule, we expressed our concern that ACOs that serve a large portion of beneficiaries dually eligible for Medicare and Medicaid and the Medicare Part D LIS may receive lower quality scores during the switch to eCQMs without an adjustment and, in turn, be incentivized to avoid these populations, delay switching to eCQMs for as long as possible, or even cease participation in the Shared Savings Program altogether (87 FR 69839)