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February 2023

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The simultaneous targeting of GIP and GLP-1 receptors delivers superior clinical outcomes compared to single-agonist alternatives, while robust regulatory approval provides market confidence and development pathway clarity

The results demonstrated that CJC-1295 produced dose-dependent increases in mean plasma GH concentrations and GH secretion pulse amplitude that persisted for up to 6 days or more after a single injection

Liu C, Mo L-H, Feng B-S, Jin Q-R, Li Y, Lin J, et al

These sequence changes reduce binding to IGF-binding proteins (IGFBPs) and support sustained availability in experimental models