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This process is primarily executed by members of the gasdermin family, most notably gasdermin D (GSDMD), which is activated by inflammatory caspases in both canonical and non-canonical inflammasome pathways 51

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Nitric oxide, a gaseous neurotransmitter, is synthesized from L-arginine through different isoforms of nitric oxide synthase (NOS): Neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) (7)