In rare cases, chelation therapy can place stress on the kidneys, especially at higher doses or in individuals with pre-existing kidney issues
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3.3.2 Iron overload under high glucose promotes ROS generation and triggers ferroptosis HG disrupts iron homeostasis: upregulated TFR1 (iron uptake) and downregulated FTH1 (iron storage) lead to LIP expansion (129, 130)
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