Thus, estrogen might prevent bone loss by enhancing oxidant defenses in bone

10.33549/physiolres.931913 Glossary ENaCalpha epithelial sodium channel5-HTserotoninACEangiotensin converting enzymeACEIangiotensin converting enzyme inhibitorAchacetylcholineADHanti-diuretic hormoneADMETabsorption, distribution, metabolism, excretion and toxicityALTalanine transaminaseAngangiotensinARarteriolar resistanceARBangiotensin receptor blockerASatherosclerosisASTaspartate aminotransferaseBBbeta-blockerBKbradykininBMIbody mass indexBPblood pressureCacalciumCAcardiac arrhythmiaCAIcarbonic anhydrase inhibitorcAMPcyclic adenosine monophosphateCBVDcerebrovascular diseaseCCcalcium channelCCBcalcium channel blockercGMPcyclic guanosine monophosphateCHDcoronary heart diseaseCHFcongestive heart failureCHTcardiac hypertrophyCOcardiac outputCOXcyclooxygenaseCRCconcentration-response curveCVcardiovascularCVDcardiovascular diseaseCVScardiovascular systemDAGdiacylglycerolDBPdiastolic blood pressureDLdyslipidemiaDMdiabetes mellitusDPP-4dipeptidyl peptidase-4ECsendothelial cellsEDHFsendothelium-derived hyperpolarizing factorsEDRFendothelium-derived relaxing factorEDVend-diastolic volumeEFendothelial functioneNOSendothelial nitric oxide synthaseETendothelinFAsfatty acidsFDAFood and Drug AdministrationFMoHFederal Ministry of HealthFTIRfourier-transform infraredGABAgamma-aminobutyric acidGFRglomerular filtration rateGRASgenerally regarded as safeGTglucose toleranceH 2 Shydrogen sulfideHAheart attackHbA1chemoglobin A1c (Glycated hemoglobin)HChypercholesterolemiaHDLChigh-density lipoprotein cholesterolHFheart failureHO-1heme oxygenase 1HPhyprepolarizationHRheart rateHTNhypertensionICAM-1intracellular adhesion molecule 1IKK-Binhibitor of the nuclear factor kappa-B sub-unit betaiNOSinducible nitric oxide synthaseINRinternational normalized ratioIP 3 inositol-1,4,5-triphosphateIRinsulin resistanceIRS-1insulin receptor substrate 1KpotassiumLC 50 median lethal concentrationLD 50 medial lethal doseLDLClow-density lipoprotein cholesterolLFTliver function testMAPmean arterial blood pressureMCmyocardial contractilityMCVmean corpuscular volumeMImyocardial infarctionmiRNAmicroRNAMPmedicinal plantMSmetabolic syndromeNAnoradrenalineNCDsnon-communicable diseasesNEnorepinephrineNKCCNa + /K + /2Cl - co-transporterNOnitric oxideNOAELno-observed-adverse-effect-levelNOELno-observed-effect levelNrf2nuclear factor-erythroid 2 related factor 2NSnephrotic syndromeOSoxidative stressPDEphophodiesterasePEphenylephrinePGprostaglandinPI3-k/Aktphosphotidylinositol 3-kinase (Protien kinase B)PKCprotein kinase-CPNSparasympathetic nervous systemPPARperoxisome-proliferator-activated receptorsPTprothrombine timePVDperipheral vascular diseasePVRperipheral vascular resistanceRAASrenin-angiotensin-aldosterone systemRBCrRed blood cellRCTrandomized control trialRIrenal insufficiencyROCCreceptor-operated calcium channelROSreactive oxygen speciesRSnHhydropolysulfideRxtreatmentsGCsoluble guanylyl cyclaseSHRspontaneously hypertensive ratSMsmooth muscleSNSsympathetic nervous systemSVstroke volume,T2DMType 2 diabetes mellitusT3triiodothyronineT4thyroxineTCtotal cholesterolTGtriglycerideVCAM-1vascular cell adhesion molecule-1VDvascular dysfunctionVDCCvoltage-dependent calcium channelVFvascular functionVGCCvoltage-gated calcium channelVRvenous returnVSCCvoltage-sensitive calcium channelVSMCsvascular smooth muscle cellsWBCwhite blood cellWHOWorld Health OrganizationZnzinc Summary Keywords hypertension, medicinal plants, pharmacological, anti-hypertensive, nutraceuticals, compounds, policy, Ethiopia Citation Nureye D, Tadege G, Dubale S, Kebebe D, Suleman S and Nguelefack-Mbuyo EP (2025) Medicinal plants administered to control hypertension in Ethiopia: ethnomedicine, pharmacology, nutraceutical, phytochemistry, toxicology, and policy perspectives

It exists in virtually every cell, with the highest concentrations found in the liver (up to 10 mM), where it plays a central role in detoxification, and in the lungs, kidneys, and brain [2][3]
The predominant mechanism is attributed to its antioxidant properties that confer protection against oxidative damage, in an attempt to reestablish equilibrium in the respiratory tract
Gently pat and press until fully absorbed, morning and evening for best results
Cincinnati, OH), according to the manufacturer's instruction