Summary: There is no absolute upper age limit for weight loss injections in the UK, but clinical experience in patients aged 75 and over is limited and prescribing requires individualised assessment
Where does the available human evidence sit on the study design hierarchy: case report (low grade), retrospective series, or controlled trial (higher grade)
Eli Lillys orforglipron is the furthest advanced, in late-stage clinical trials with potential FDA approval in 2026
The trade-off is that glucagon agonism is the arm most likely to nudge metabolic parameters in directions that need watching (heart rate and glycemic dynamics among them), which is another reason the documented protocol climbs slowly and why the class monitoring guidance below is not optional context
Pharmacies recommend keeping unmixed HCG in a cool place that is out of light
During the day I also plug that (practice) into moments where I'm kind of feeling off or a little down