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Sertraline (1 M) inhibits the HMGB1/toll-like receptor 4 (TLR4)- and TNF-/TNF receptor 1 (TNFR1)-mediated nuclear factor-kappa B (NF-B) activation in HMGB1- or TNF--stimulated microglia [3]

Pooled hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using a random-effects model, with subgroup analyses by cancer type and exposure duration

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Passed: Validates the formulations acid/base balance to support comfortable administration