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Seveljevic-Jaran et al., 2006

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Additionally, it inhibits fatty acid synthase expression by activating the AMPK pathway, thus inhibiting fatty acid synthesis [188, 189]

Additionally, all three compounds increased antioxidant enzyme activity (SOD, APX and CAT), with melatonin showing the highest increases (25 %, 42.86 % and 31.5 %)

A more accurate assessment of these values was not possible due to low solubility of these compounds at high micromolar concentrations

Oxidative stress-induced glutathionylation has been recognized as a mechanism for induction and regulation of several proteins, including Grx (glutaredoxin), Trxs (thioredoxin) and GSTs, which are involved in environmental stress responses (Dixon et al