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Recently, HDL have been reported to transport miRNA (Figure 10), which are small non-coding RNAs that suppress gene expression through binding to complimentary target sites in the 3 untranslated region of mRNAs, and thus inhibit translation and induce mRNA degradation (772)

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Both produce therapeutic CNS concentrations, but subcutaneous allows for longer intervals between observable plasma peaks, which may reduce variability in studies measuring acute cognitive effects

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