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Eli Lilly and Company originally applied TZT to control blood glucose in 2016

In addition, GLP-1 causes delayed gastric emptying, which leads to weight loss [43]

The most common side effects are nausea, vomiting, loose motions, constipation, stomach pain and reduced appetite

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Some patients have reported severe abdominal pain, hospitalization for acute pancreatitis, and permanent gastrointestinal dysfunction following excessive dosing or rapid escalation