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The SELECT trial found that overweight or obese patients with CVD reduced their risk of MACE on GLP-1s

Long-term changes in cardiovascular risk markers during administration of exenatide twice daily or glimepiride: results from the European exenatide study

Cash-pay and telehealth options Direct-pay telehealth platforms have emerged as another pathway to GLP-1 access

That difference is not considered clinically significant for most patients

Women should not take GLP-1s or other weight loss medications while pregnant, breastfeeding, or trying to conceive

However, the first week is typically more about the body adjusting to the medication rather than seeing significant changes on the scale