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Both medications can cause gastrointestinal side effects, so combining them may increase the likelihood of digestive symptoms, particularly when starting treatment

Svane MS, Jorgensen NB, Bojsen-Moller KN et al (2016) Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

Novo is not alone in ramping up production, with the recent launch of a $27B manufacturing initiative from Eli Lilly

Reported or potential effects include: Hypoglycemia: IGF-1 enhances glucose uptake by muscles, which can occasionally lead to transient low blood sugar, especially when fasting or undernourished

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