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Protein-protein interaction (PPI) network analysis was conducted using Cytoscape V3.10.1 software

HSPGs have a role in several pathways in dopaminergic cells (Figure 1), such as being an essential modulator in diencephalon spinal mechanisms of DA cells (Kastenhuber et al., The Ca +2 flux between the endoplasmic reticulum and mitochondria is mediated by the AKT pathway

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All patients were extubated when they were able to maintain spontaneously a PaO2/FIO2 ratio of more than 400

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