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even lower exposure beat placebo for weight loss in early trials. The 2.4 mg maintenance dose sits on the shoulder of the effect curve rather than at a hard ceiling

oxidative sperm damage from low levels impairs motility, as seen in subfertile men

The magnitude of weight loss observed with GLP1-RA in this real-life patient population is consistent with findings from the SCALE, SUSTAIN, and STEP clinical trials, which are based on patients without bariatric surgery

The degree of disability after stroke did not differ by treatment group

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