*Correspondence: Nils Wierup, [email protected] Specialty section: This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The clinical trials reported tirzepatide to be well-tolerated
So when patients began asking me about peptidescompounds buzzing through wellness circles with promises of enhanced healing, improved body composition, and anti-aging benefitsI'll admit my initial reaction was skepticism
Your GP should monitor: Weight trends and body composition changes Blood glucose and HbA1c levels Blood pressure (both medications can influence cardiovascular parameters) Electrolyte balance (prednisolone can cause hypokalaemia) Bone health if long-term corticosteroid use is anticipated (following NOGG guidance for glucocorticoid-induced osteoporosis risk assessment and prophylaxis) Never stop either medication without medical guidance
Consistently exercise
Microdosing GLP-1 means using a lower-than-standard dose, but long-term effectiveness hasnt been confirmed in large clinical trials