The medication should be avoided during pregnancy and breastfeeding, and stopped sufficiently in advance of planned pregnancy according to medical advice
*N/A: RI has not been established
In the ascorbic acid group, 13/15 (86.7%) of the lesions had completely disappeared after 8 weeks, but with IMQ the lesions disappeared only in 8/14 (57.1%) cases
Tosaki, K
However, these studies were limited by the toxicity of H 2 O 2 and the poor tissue permeability of BxxP, a membrane-impermeant variant of BP required to prevent labeling of intracellular ER and Golgi proteins by surface-targeted HRP 3
A stepwise, detailed description of the 3Ts protocol follows, constituting, to our knowledge, the first fully specified Peyronies disease management protocol