not a weight-loss driver Option GLP-1 (semaglutide, tirzepatide) What it is FDA-approved weight-management drugs Evidence for weight loss Strong RCT evidence (SURMOUNT, STEP) Lipo-C sits at the low-evidence end
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Semaglutide for Weight Loss Among the newest entrants in the world of weight management is the drug semaglutide
Initially FDA-approved for the management of type 2 diabetes, these drugs are now a viable solution for weight loss because they mimic the hormone GLP-1 to increase feelings of fullness, slow gastric emptying, and stimulate insulin release, while targeting brain receptors that help reduce cravings and hunger
Nature 536 , 446450 (2016)
As a result, reducing these factors can be indicated an improvement in the disease process