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MAPK pathway The mitogen-activated protein kinase (MAPK) family is a large group of proteins, which are involved in intracellular signal transduction and control basic cellular functions such as differentiation, response to stress, and apoptosis (Plotnikov et al

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Tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for weight management, is a dual GIP/GLP-1 receptor agonist that has transformed metabolic disease treatment

Conclusions The cases of suicide or self-injury reported to FAERS do not indicate any overall safety signal attributable to GLP-1RA at this time

Pharmacopsychiatry 43 :24-32