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The two are distinct phenomena with different mechanisms and different management approaches

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"GLP-1 medications explained: Benefits, risks and how they work." scrubbingin , Baylor Scott &White Health, 15 Oct

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In these STEP trials, most participants experienced mild to moderate symptoms, with the incidence of severe side effects being 9.8% in the semaglutide treatment group and 6.4% in the placebo group