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The new decision comes after a lawsuit filed by compounders forced the FDA to announce it was reviewing its original decision from October

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In emergency treatment of acquired methemoglobinemia (typically using IV MB), the dose is weight-based, usually 1-2 mg/kg intravenously, which for an average adult (70 kg) is on the order of 70-140 mg administered once and can be repeated once if needed

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For patients with established atherosclerotic cardiovascular disease, injectable agents with proven outcome data may still be preferred