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Hence, pharmaceuticals that target the NRF2 pathway can influence multiple pathways involved in the neurodegenerative process, and therefore hold potential to become therapies that can significantly modify the course of neurodegenerative diseases

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[98] This radical then reacts with NADH, to produce adducts that are very potent inhibitors of the enzymes enoyl-acyl carrier protein reductase, [99] and dihydrofolate reductase

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She tried hormone replacement therapy and strength training, which she says helped stabilize her sleep, hot flashes, and weight