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Shaun Sabico and Yousef Al-Saleh wrote the manuscript

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El tercer estudio demostr que el uso de cido flico en forma preconcepcional permita tambin disminuir el riesgo de ocurrencia, puesto que en el grupo suplementado no ocurri ningn caso de DCTN, a diferencia del grupo control en el que se observ una ocurrencia cercana a 3 por 1 000, similar a la esperada para la poblacin general