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GH-Axis : Due to age-related decline in pituitary function, older adults may require a longer cycle duration (16-24 weeks) and may need to use the standard or advanced doses of GHSs to achieve a therapeutic effect

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Although interest in these compounds has grown within the biohacking and antiaging communities, their applications may also be relevant in orthopaedic recovery

For research institutions designing protocols, this context is essential: the compounds therapeutic potential is supported by a large body of animal research, but translation to human outcomes remains an active area of investigation rather than established clinical fact