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In clinical trials, approximately 70% of participants reportedly exhibited adverse events, primarily gastrointestinal symptoms, such as diarrhea and nausea

Improvements in blood sugar, blood pressure, cholesterol, and hormonal symptoms like those linked to PCOS may be a reason to continue treatment longer-term, even after reaching a target weight

These involuntary contractions of the esophagus can lead to intense pain that may mimic the sensation of a heart attack

Furthermore, because weight loss does not occur at once, normalizing EE to a fluctuating factor can be problematic

Some people go a full 24 hours without eating once or twice a week, but a common method is daily time-restricted eating