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While some doctors have anecdotally reported similarly positive experiences in their patients who switched to a slower schedule, the studys results are limited: The sample size is quite small, for one, and more work in larger and more diverse groups will be needed to understand if different dosing schedules could help more people stay on their medication, without getting the pukes.

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Single-cell transcriptomic profiling of CTCs collected during resting phases reveals elevated mitotic activity, providing a mechanistic basis for time-dependent metastatic potential and underscoring the importance of chronobiology in cancer diagnosis and therapy (176)

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