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Response: We appreciate commenters' concerns regarding our proposal to grant ECEs to hospitals, REHs, and ASCs that have not requested an ECE but were subject to an extraordinary circumstance affecting their region or locale

And no significant horizontal pleiotropy and heterogeneity was detected based on the outcomes of MR-Egger outcomes

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Patients were categorized into Rt or Lt groups of ischemic area, and the efficacy of EVT was assessed in Rt and Lt groups separately

The study was prompted after senior author Dr