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Although this adaptive change temporarily maintains energy supply, it can lead to long-term mitochondrial bioenergetic dysfunction and reduced OXPHOS efficiency, thereby affecting the energy metabolic homeostasis of distant organs via the circulatory system

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Even considering all of these factors you need to understand that checking vitamin B12 levels in the serum still isnt the best way to evaluate for B12 deficiency

A recent study on insomnia in peri- and postmenopausal women observed a significant decrease in GSH levels among postmenopausal participants [24]