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Despite the enrichment of several hair growth-related pathways, we focused on validating the Wnt/-catenin pathway due to its established role in hair follicle biology, the specific enrichment of canonical Wnt signaling, and the strong representation of its target genes

This requirement of ECL1 recognition drives the above six key positions in dual or triple agonists (tirzepatide, peptide 20 (MAR423), and retatrutide) to use amino acids similar to those in GLP-1/GCG, while the other positions in the middle region show considerable variability (Fig

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279 These data confirmed the powerful ability of cfDNA/ctDNA as a diagnostic tool for primary breast cancer

The transcription factors smad, zeb1/2, snail, slug, and twist are key drivers of the EMT program