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Diarrhea is one of several digestive symptoms patients may experience when taking semaglutide

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The trials employed randomised, placebo-controlled designs with single ascending dose (SAD) and multiple ascending dose (MAD) protocols

Studies examine how activating all three pathways simultaneously influences metabolic outcomes

New numbness, wrist pain, or worsening sleep apnea symptoms should be discussed with a clinician

Data are least squares mean (standard error) from mixed-model repeated measures for change in A ) pre-lunch appetite VAS scores, B ) Food Craving Inventory, C ) Food Craving Questionnaire-State, D ) Eating Inventory, and E ) Power of Food Scale, at week 3 in all randomized participants (placebo, n = 39