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Some researchers propose that B12 influences neurotransmitter metabolism in the chemoreceptor trigger zone of the brainstem

IRP can bind to the iron response element (IRES) in mRNA encoding key iron regulatory proteins, including DMT1, ferritin heavy chain (FTH), TfR1, and ferritin, thereby stabilizing iron absorption, utilization, storage, and output (18)

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122 SultanaMRBagulPKKatarePBAnwar MohammedSPadiyaRBanerjeeSK

J Neurosci 2001