It activates Gasdermin D (GSDMD)-dependent pyroptosis and inhibits SLC7A11 through the Stat3/p53/NRF2 pathway, thereby inducing ferroptosis (94)
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Metabolic research compounds are reference materials studied in preclinical models of energy metabolism NNMT inhibition, ERR agonism, AMPK activation and related signalling used in exercise-mimetic research
These metabolites, including flavonoids (e.g., quercetin, baicalin), saponins (e.g., ginsenosides, astragalosides), alkaloids (e.g., berberine, matrine), and others like polyphenols and terpenoids, exhibit a remarkable breadth of cardioprotective actions
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