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Tirzepatide (trade name Mounjaro) is a new glucose-lowering medicine in the incretin family which, to date, has included the glucagon-like peptide-1 (GLP-1) receptor agonists (such as dulaglutide and semaglutide) and dipeptidyl peptidase-4 (DPP-4) inhibitors (including linagliptin and sitagliptin)

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Moreover, this comprehensive structural biophysical analysis [50] also identified two hydrogen bonds the binding interface of semaglutide and GLP-1R ECD [29, 52], as listed in Table 2

Zimmerman, J

It plays a key role in building protein molecules together with critical bodily functions including the production of red blood cells, nerve cells and DNA

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