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Functional enrichment (GO/KEGG) and Gene Set Enrichment Analysis (GSEA) revealed that GGCT knocking down significantly impacted pathways related to the cell cycle, oxidative stress, cell proliferation, and cell death in both cancers (Fig

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mTOR inhibition Rapamycin is a well-studied FDA approved immunosuppressive drug that has been shown to extend lifespan in yeast, worms, flies, and mice (83, 84)

Warnings: It is used as a food supplement only and is not considered a substitute for a balanced diet

Optimize fasting protocols: Maintain standard fasting windows of 8 hours for solids and 6 hours for clear fluids, extending to 12 hours in symptomatic or high-BMI patients