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The expression of CYP2J, a member of P450 subfamily with a role in the bioactivation of AA in extrahepatic tissues, inhibits NF-B and MAPK signaling pathways and activates of PPAR, thus reducing IR and diabetic phenotype [173]
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The samples were vortexed 15 s and left in a freezer at -20 C for 60 min, followed by centrifugation at 21,100 RCF for 15 min at 4 C
10.1038/bjc.2017.96 13 HarrisI
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JCI Insight 5, e142272
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