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the reduced dye then undergoes non-enzymic oxidation in air, so the addition of a relatively small amount of methylene blue will effectively deplete NADPH, and would be expected to stimulate any pathway that reduces NADP+ to NADPH

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For more information please read Legend 2 mL Product Information , Legend 4 mL Product Information , and Legend Multi-dose 20 mL Product Information

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A few commenters noted under this method, hospitals may be labeled as low performers even if they demonstrate strong safety outcomes, while hospitals ranked in the top quartile may not necessarily meet high safety benchmarks

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