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Pharmacokinetics and cellular uptake of Imatinib and its main metabolite CGP74588

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Mechanistically, Myc drives glutaminolysis by upregulating GLUD1 and induces a concurrent increase in the expression of GLS and SLC1A5 24

In OS-induced senescence models, PERK-mediated upregulation of CCAAT/enhancer-binding protein homolog occurs (54)

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