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The anabolic actions of IGF1 have been exploited for therapeutic purposes by using IGF1 administration to treat short children who are resistant to the growth promoting effects of growth hormone

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Even with statin therapy for dyslipidemia, individuals with EOT2D continue to exhibit a significant burden of atherogenic apolipoprotein particles compared to those with later-onset T2DM, though the long-term consequences remain unknown [52]

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This structural feature enables controlled as well as sustained release of drugs specifically within tumor microenvironment (TME), improving therapeutic efficiency while reducing systemic adverse effects (Chen et al