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The failure to achieve normal PRL or lack of relevant tumor shrinkage ( 30% in maximum diameter or 50% in volume) when treated with standard DA doses (10 mg per day of BRC or 2 mg per day of CAB) at least 6 months is defined as DA resistance (200)

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Data were analyzed by analysis of variance (ANOVA) methods, utilizing a mixed model including sequence and period effect in the model

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Improvement of Metabolic Parameters : Both probiotics and GLP-1 receptor agonists positively influence metabolic health by improving insulin sensitivity and lipid profiles