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Recently, it has become widely accepted that tumor cells may coat themselves with sialic acid to induce immune escape via engagement with several Siglecs, meaning Siglecs act as immune checkpoints (244)

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A recent meta-analysis including all seven GLP-1RA CVOTs, that is, 42,920 patients, showed a 12% relative risk reduction in MACE during GLP-1RA treatment compared to placebo

M., Martin, G

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If already on GLP-1: What is the exit or taper plan how will we maintain gains, preserve lean mass, and stabilize appetite and hormone balance long-term