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Severe or persistent abdominal pain, especially if radiating to the back and accompanied by nausea or vomiting, may indicate acute pancreatitisa serious adverse effect requiring emergency evaluation

Dulaglutide has not been studied in patients with a history of pancreatitis

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Xiao YF, Nikolskaya A, Jaye DA, Sigg DC (2011) Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway

As recently as FY2024 the two sat less than $3 billion apart