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The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]

doi:10.1053/j.gastro.2022.08.045

Consult a doctor before use if you have specific medical conditions

Interestingly, these patients had a lower AUC HIE than the hyperinsulinemic subjects in baseline conditions, but a higher one after 24 weeks

The trial design was unusual

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