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Daily oral orforglipron (Foundayo): Weekly injectable semaglutide for weight loss (Wegovy) : Average weight loss of 14.9 percent of body weight after about 15 months, compared with 2.4 percent in a placebo group Average weight loss of 21 percent of body weight after about 16 months, compared with 3.1 percent in a placebo group Weekly injectable tirzepatide for weight loss (Zepbound): Secondary Health Benefits Though this entire family of drugs has benefits for metabolic health, not every particular drug has been approved for the same conditions

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