The Bro Optimization Economy is here and its spilling over into mainstream
This narrative review covers the identification and development of incretin therapy for diabetes and obesity, culminating in the recent clinical trials of dual agonist therapy and the future prospect of tri-agonists
Clinical trials and real-world data consistently show: Average weight loss of 1520% on semaglutide or tirzepatide Improvements in blood pressure, cholesterol, and blood sugar Reduced risk of developing type 2 diabetes and cardiovascular disease These outcomes are meaningful both for employee health and long-term cost avoidance

In a 90-day user survey, participants reported via a survey they lost an average of 18 lbs., or 9% of their body weight, by using the Complete Body Transformation Collection in conjunction with healthy diet and exercise. Day 1: Physical Satiety Decreased appetite* Decreased hunger cravings* Increased caloric burn* Boosted metabolism* ~30 Days: GLP-1 Induction Support for GLP-1 support* Support for blood sugar levels already within normal range* Changes in fat metabolism when combined with diet and exercise* Reduction in the appearance of cellulite when combined with diet and exercise* ~90 Days: Microbiome Adjustment Support for Akkermansia colonization in the gut* Improvement in fat-to-muscle ratio with exercise* Reduction in hip, waist and thigh circumference when combined with diet and exericse* Your Wellness Guide to GLP-1 Support & Healthy Weight Management* At Modere, we believe that not knowing where to start is the last thing that should stand in the way of your wellness journey

Key Takeaways: Best Supplements to Take While on GLP-1 GLP-1 medications can be powerful tools for supporting weight loss and overall health, if done right
10.1016/j.physbeh.2009.02.009 22 DiakogiannakiE.GribbleF