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Critically, though dysbiosis worsens chronic inflammation by promoting pathogen dominance and biofilm tenacity, emerging data indicate that recapitulating microbial balance through targeted interventions may curtail AMR

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Third, age-related mitochondrial dysfunction is another key contributor

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Acknowledgments AKP acknowledge University Grant Commission-SAP and DST-FIST facilities of the Biochemistry Department, University of Allahabad, Prayagraj Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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