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59,70,105 The best characterized member is SIRT1, which has been associated with longevity

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In lean adult mice, the expression of NDI1 in adipocytes had no impact on body weight, glucose homeostasis, the expression of mature adipocyte and thermogenic markers, or histological features of adipose depots (Extended Data Fig

Introduction Patients affected by chronic kidney disease (CKD) or end-stage renal disease (ESRD) have a shorter life expectancy than those with normal renal function, primarily due to the dramatic increase in cardiovascular mortality [1]

Nov-Dec 1982;1(6):529-33